Water → 5-(p-Aminophenyl)-1-(p-bromophenyl)-1H-1,2,4-triazole

HRID 128456Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 128456
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=3)=[N:11][CH:10]=[N:9]2)=[CH:4][CH:3]=1.S(S([O-])=O)([O-])=O.[Na+].[Na+].O>CC(C)=O>[NH2:19][C:16]1[CH:17]=[CH:18][C:13]([C:12]2[N:8]([C:5]3[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=3)[N:9]=[CH:10][N:11]=2)=[CH:14][CH:15]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 24489Sodium DithioniteHCID 12676668HCID 12676668, Verbindung

Produkt 1

HCID 126766735-(p-Aminophenyl)-1-(p-bromophenyl)-1H-1,2,4-triazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

A mixture of 9.0 g. of 1-(p-bromophenyl)-5-(p-nitrophenyl)-1H-1,2,4-triazole, 18.0 g. of sodium hydrosulfite, 40 ml. of water and 150 ml. of acetone is stirred at room temperature overnight. The acetone is removed in vacuo and the residue is extracted with hot chloroform. Cooling produces 2.1 g. of the desired product as pale yellow crystals, mp. 128°-130° C.

Aufarbeitung

  1. additionA mixture of 9.0 g
  2. customThe acetone is removed in vacuo
  3. extractionthe residue is extracted with hot chloroform
  4. temperatureCooling
  5. customproduces 2.1 g

Quellen und Nachweise

ORD-Eintrag
ord-01176273fad3487795740cd5ce94da69
Quelldatensatz
uspto-grants-1981_03
Patentnummer
US04259504

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