Morpholine → 4-(4-Trifluoromethylphenyl)morpholine

Reaktionsgleichung

C1COCCN1.FC(F)(F)c1ccc(Br)cc1>CN(C)c1ccccc1P(C(C)(C)C)C(C)(C)C.COCCOCCOC.C[O-].O=C([O][Pd][O]C(=O)C(F)(F)F)C(F)(F)F.[Na+]>FC(F)(F)c1ccc(N2CCOCC2)cc1

customThe foil sealing tape was removed from the plate.
addition3 μL of a 0.0667 M solution of caffeine in DMSO was added to each reaction well using an SPT Labtech Mosquito® liquid handling robot
filtrationThe plates were then centrifuged for 15 to 20 seconds. · liquid-Phase beibehalten
aliquotFollowing centrifugation, 500 nL of the resultant mixture from each well was carefully dispensed into four 384-well analytical plates (Analytical Sales # 38435) using an SPT Labtech Mosquito® liquid handling robot. Each well of these analytical plates contained 30 μL of DMSO with 0.1% acetic acid, pre-dosed by OpenTrons, to facilitate analysis.

ORD-Eintrag: ord-1c457e2e8b204a7485512c0eb2962209
Quelldatensatz: High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
DOI: 10.1021/jacs.6c05959
Originallink: Quelle ansehen

Wird geladen…

customThe foil sealing tape was removed from the plate.
addition3 μL of a 0.0667 M solution of caffeine in DMSO was added to each reaction well using an SPT Labtech Mosquito® liquid handling robot
filtrationThe plates were then centrifuged for 15 to 20 seconds. · liquid-Phase beibehalten
aliquotFollowing centrifugation, 500 nL of the resultant mixture from each well was carefully dispensed into four 384-well analytical plates (Analytical Sales # 38435) using an SPT Labtech Mosquito® liquid handling robot. Each well of these analytical plates contained 30 μL of DMSO with 0.1% acetic acid, pre-dosed by OpenTrons, to facilitate analysis.

ORD-Eintrag: ord-1c457e2e8b204a7485512c0eb2962209
Quelldatensatz: High-throughput exploration of 50,688 Pd-, Ni- and Cu-catalysed C–N coupling reactions
DOI: 10.1021/jacs.6c05959
Originallink: Quelle ansehen

Wird geladen…