Acetic Acid → (S)-2-((S)-3-acetamido-3-((R)-sec-butyl)-2-oxopyrrolidin-1-yl)-N-((1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-((R)-morpholin-3-yl)propan-2-yl)-4-phenylbutanamide

Reaktionsgleichung

C(N[C@]1([C@@H](CC)C)CCN([C@@H](CCC2C=CC=CC=2)C(N[C@@H](CC2C=C(F)C=C(F)C=2)[C@@H]([C@H]2C[C@@H](O)CN2C(C2C=CC=CC=2)C2C=CC=CC=2)O)=O)C1=O)(=[O:3])C.[C:58]([NH:61][C@:62]1([C@@H:111]([CH2:113][CH3:114])[CH3:112])[CH2:66][CH2:65][N:64]([C@@H:67]([CH2:102][CH2:103][C:104]2[CH:109]=[CH:108][CH:107]=[CH:106][CH:105]=2)[C:68]([NH:70][C@@H:71]([CH2:93][C:94]2[CH:99]=[C:98]([F:100])[CH:97]=[C:96]([F:101])[CH:95]=2)[C@@H:72]([C@H:74]2[CH2:79]CCC[N:75]2[CH:80]([C:87]2C=CC=CC=2)C2C=CC=CC=2)[OH:73])=[O:69])[C:63]1=[O:110])(=[O:60])[CH3:59].C(O)(=O)C.[H][H]>CO.[Pd]>[C:58]([NH:61][C@:62]1([C@@H:111]([CH2:113][CH3:114])[CH3:112])[CH2:66][CH2:65][N:64]([C@@H:67]([CH2:102][CH2:103][C:104]2[CH:105]=[CH:106][CH:107]=[CH:108][CH:109]=2)[C:68]([NH:70][C@@H:71]([CH2:93][C:94]2[CH:99]=[C:98]([F:100])[CH:97]=[C:96]([F:101])[CH:95]=2)[C@H:72]([OH:73])[C@H:74]2[CH2:79][O:3][CH2:87][CH2:80][NH:75]2)=[O:69])[C:63]1=[O:110])(=[O:60])[CH3:59]