Acetic Acid → Methyl 4-(2-acetylhydrazino)benzoate

HRID 133174

Reaktionsgleichung

Reaktionsgleichung von HRID 133174
[NH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)[NH2:2].[CH3:13][C:14](O)=[O:15]>C([O-])(=O)C.[Na+]>[C:14]([NH:2][NH:1][C:3]1[CH:4]=[CH:5][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:11][CH:12]=1)(=[O:15])[CH3:13]

Komponenten

4

Edukt 2

HCID 176Acetic AcidHCID 408928Methyl 4-hydrazinylbenzoate

Produkt 1

HCID 12765612Methyl 4-(2-acetylhydrazino)benzoateAusbeute 115,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 517045Sodium AcetateLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

5.5 g of methyl 4-hydrazinobenzoate are dissolved in 38.2 ml of AcOH comprising 2.4 g of sodium acetate and the mixture is heated at 80° C. for 18 hours. The inorganic material is filtered off, the filtrate is then evaporated and the residue is taken up in the minimum amount of Et2O. The mixture is filtered to produce 7.97 g of the expected compound.

Aufarbeitung

  1. filtrationThe inorganic material is filtered off
  2. customthe filtrate is then evaporated
  3. filtrationThe mixture is filtered

Quellen und Nachweise

ORD-Eintrag
ord-07f58774b4744ce2b08cb56ac6cf1c96
Quelldatensatz
uspto-grants-2008_06
Patentnummer
US07390818B2

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