Water → 4-Hydrazinobenzenesulfonic acid morpholide

HRID 1358376Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1358376
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[CH2:16][CH2:15][O:14][CH2:13][CH2:12]2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.O.[NH2:18][NH2:19].O>CN1CCCC1=O>[NH:18]([C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[CH2:16][CH2:15][O:14][CH2:13][CH2:12]2)(=[O:10])=[O:9])=[CH:4][CH:3]=1)[NH2:19]

Komponenten

5

Edukt 3

HCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 7553774-((4-Fluorophenyl)sulfonyl)morpholine

Produkt 1

HCID 112998664-Hydrazinobenzenesulfonic acid morpholide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 13387N-methyl-2-pyrrolidoneLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

5 g of 4-fluorobenzenesulfonic acid morpholide were dissolved in 15 ml of N-methylpyrrolidone and mixed with 2.5 g of hydrazine hydrate, and the mixture was heated at 100° C. for 1 hour. After cooling to room temperature, 75 ml of water were added and the mixture was stirred at room temperature. After 2 hours, the solid was filtered off with suction and recrystallized from isopropanol.

Aufarbeitung

  1. temperatureAfter cooling to room temperature
  2. filtrationthe solid was filtered off with suction
  3. customrecrystallized from isopropanol

Quellen und Nachweise

ORD-Eintrag
ord-32059fe74de94fbab9455921df158db1
Quelldatensatz
uspto-grants-2003_07
Patentnummer
US06596742B1

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