1,3-Cyclohexanedione → 2-Bromocyclohexane-1,3-dione

HRID 1364080Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1364080
[C:1]1(=[O:8])[CH2:6][CH2:5][CH2:4][C:3](=[O:7])[CH2:2]1.[Br:9]Br>CC(O)=O>[Br:9][CH:2]1[C:3](=[O:7])[CH2:4][CH2:5][CH2:6][C:1]1=[O:8]

Komponenten

4

Edukt 2

HCID 104341,3-CyclohexanedioneHCID 24408Bromine

Produkt 1

HCID 27704762-Bromocyclohexane-1,3-dione

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

To a stirred solution of cyclohexane-1,3-dione (1.12 g, 10 mmol) in AcOH (20 mL) at r.t. was added bromine (1.6 g, 0.51 mL, 10 mmol) dropwise. The reaction mixture was stirred for 2 h and then the product was isolated by filtration. The precipitate was washed twice with Et2O (100 mL) and then dried in vacuo to give the title compound in quantitative yield as a buff solid, which was used without further purification. LCMS (ES+) 190.9 (M+H)+.

Aufarbeitung

  1. customthe product was isolated by filtration
  2. washThe precipitate was washed twice with Et2O (100 mL)
  3. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-71186469f40b42658d4deaa0c35056b0
Quelldatensatz
uspto-grants-2011_02
Patentnummer
US07888344B2

Notizen zur Reaktion

Wird geladen…