Nitrobenzene → 1-(4-Nitrophenyl)-4-imidazolidinone

HRID 1373165Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1373165
[NH:1]1[CH2:5][C:4](=[O:6])[NH:3][CH2:2]1.[N+:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)([O-:9])=[O:8].C(N(C(C)C)CC)(C)C>CN(C=O)C>[N+:7]([C:10]1[CH:15]=[CH:14][C:13]([N:1]2[CH2:5][C:4](=[O:6])[NH:3][CH2:2]2)=[CH:12][CH:11]=1)([O-:9])=[O:8]

Komponenten

5

Edukt 3

HCID 7416NitrobenzeneHCID 81531DiisopropylethylamineHCID 15020634-Imidazolidinone

Produkt 1

HCID 210742741-(4-Nitrophenyl)-4-imidazolidinone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

A solution of 4-imidazolidinone (9.5 g, 110.5 mmol), 4-nitrobenzene (1 eq) and diisopropyl ethylamine (28.6 mL, 165 mmol) in dry DMF (80 mL) was heated to 60° C. overnight under argon. The reaction mixture was allowed to cool to room temperature and ice pieces were added. The solid formed was filtered and washed with water. The solid was air dried to yield the nitro compound as yellow crystals.

Aufarbeitung

  1. additionice pieces were added
  2. customThe solid formed
  3. filtrationwas filtered
  4. washwashed with water
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-fbcb744e7e664f68805ac3377625e719
Quelldatensatz
uspto-grants-2007_01
Patentnummer
US07160912B2

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