3-Cyano-2,6-dichloro-4-methylpyridine → 4-Methyl-3-cyanopyridine

HRID 1378689

Reaktionsgleichung

Reaktionsgleichung von HRID 1378689
[C:1]([C:3]1[C:4](Cl)=[N:5][C:6](Cl)=[CH:7][C:8]=1[CH3:9])#[N:2]>[Pd](Cl)Cl.[Pd]>[C:1]([C:3]1[CH:4]=[N:5][CH:6]=[CH:7][C:8]=1[CH3:9])#[N:2]

Komponenten

4

Edukt 1

HCID 701313-Cyano-2,6-dichloro-4-methylpyridine

Produkt 1

HCID 2278064-Methyl-3-cyanopyridine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 24290Palladium ChlorideKatalysator

Versuchsvorschrift

hydrogenating the 3-cyano-2,6-dichloro-4-methylpyridine produced in b) in the presence of an organic solvent, with an hydrogenation catalyst selected from the group consisting of palladium (II) chloride and 10% Pd/C, at 50 to 150 psi, at a temperature of from 20° C. to 100° C., for 6 to 24 hours, to produce 3-cyano-4-methylpyridine;

Aufarbeitung

  1. customproduced in b) in the presence of an organic solvent

Quellen und Nachweise

ORD-Eintrag
ord-aec8da546a4b41c18a5b9393bce6e4e7
Quelldatensatz
uspto-grants-1997_09
Patentnummer
US05668287

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