Sodium Azide → HCID 13292769, Verbindung

HRID 1382626Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1382626
Br[CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8](/[C:11](/[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[C:12](\[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)/[C:13]([F:16])([F:15])[F:14])=[CH:7][CH:6]=1.[N-:29]=[N+:30]=[N-:31].[Na+]>COCCO.O>[N:29]([CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8](/[C:11](/[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[C:12](\[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)/[C:13]([F:16])([F:15])[F:14])=[CH:7][CH:6]=1)=[N+:30]=[N-:31]

Komponenten

5

Edukt 2

HCID 33557Sodium AzideHCID 13292770HCID 13292770, Verbindung

Produkt 1

HCID 13292769HCID 13292769, VerbindungAusbeute 82,2 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 80192-MethoxyethanolLösungsmittel

Versuchsvorschrift

9.83 g (22 mmoles) of (E)-1-[4-(2-bromoethoxy)-phenyl]-1,2-diphenyl-3,3,3-trifluoro-propene are dissolved in 100 ml of 2-methoxyethanol, a solution of 2.86 g (44 mmoles) of sodium azide in 10 ml of water is added, and the mixture is boiled for one hour. The reaction mixture is processed as described in Example 5, and the product is recrystallized twice from ethanol. 7.40 g (82%) of the aimed compound are obtained; m.p.: 73°-75° C.

Aufarbeitung

  1. customthe product is recrystallized twice from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-0e07e1eb2117425781e2138323f16132
Quelldatensatz
uspto-grants-1989_02
Patentnummer
US04806685

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