Acetic Anhydride → (6-Methylpyridin-2-yl)methyl acetate

HRID 1383825

Reaktionsgleichung

Reaktionsgleichung von HRID 1383825
[C:1]([O:4][C:5](=[O:7])[CH3:6])(=O)[CH3:2].[N+:8]1([O-])C(C)=[CH:10][CH:11]=[CH:12][C:13]=1[CH3:14]>>[C:5]([O:4][CH2:1][C:2]1[CH:10]=[CH:11][CH:12]=[C:13]([CH3:14])[N:8]=1)(=[O:7])[CH3:6]

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 140832,6-Dimethylpyridine N-oxide

Produkt 1

HCID 291137(6-Methylpyridin-2-yl)methyl acetate

Reaktionsbedingungen

Temperatur
110 °C

Versuchsvorschrift

Acetic anhydride (23 ml) was heated to 110° C. and 2,6-lutidine-N-oxide (20 g) was added dropwise over 1 hour. The solution was heated at 110° C. for five hours. After cooling, the crude mixture was distilled to yield 2-acetoxymethyl-6-methylpyridine (18.4 g, b.p. 110-120° C. @ 15 mmHg).

Aufarbeitung

  1. temperatureAfter cooling
  2. distillationthe crude mixture was distilled

Quellen und Nachweise

ORD-Eintrag
ord-9d21fda086014f35a60a392747967bee
Quelldatensatz
uspto-grants-2001_07
Patentnummer
US06255305B1

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