Iodine → HCID 21706514, Verbindung

HRID 1387278

Reaktionsgleichung

Reaktionsgleichung von HRID 1387278
[CH3:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[C:3]=1[N+:9]([O-:11])=[O:10].II.[I:14]([O-])(=O)=O.[Na+].O>C(O)(=O)C.S(=O)(=O)(O)O>[I:14][C:7]1[C:2]([CH3:1])=[C:3]([N+:9]([O-:11])=[O:10])[C:4](=[O:8])[NH:5][CH:6]=1

Komponenten

7

Edukt 4

HCID 807IodineHCID 962WaterHCID 3453702-Hydroxy-4-methyl-3-nitropyridineHCID 23675764Sodium Iodate

Produkt 1

HCID 21706514HCID 21706514, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 176Acetic AcidLösungsmittelHCID 1118Sulfuric AcidLösungsmittel

Reaktionsbedingungen

Temperatur
75 °C

Versuchsvorschrift

To a solution of 4-methyl-3-nitro-2-pyridone (2.00 g, 13 mmol) in acetic acid (12 mL) and concentrated sulfuric acid (1.6 ml,) was added iodine (1.32 g) and sodium iodate (0.55 g). The mixture was heated at 75° C. for 2.5 hours and then stirred at rt overnight. Water (100 mL) was added, and the precipitated 5-iodo-4-methyl-3-nitro-2-pyridone was collected by filtration (2.97 g, 82%).

Aufarbeitung

  1. filtrationthe precipitated 5-iodo-4-methyl-3-nitro-2-pyridone was collected by filtration (2.97 g, 82%)

Quellen und Nachweise

ORD-Eintrag
ord-4e8af721267749e8b617049bd221cc3a
Quelldatensatz
uspto-grants-2001_07
Patentnummer
US06268365B1

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