Dichloromethane → 5-[2-(5-Chloro-2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-pyridin-2-ylamine

Reaktionsgleichung

[NH2:1][C:2]1[CH:7]=[CH:6][C:5](Br)=[CH:4][N:3]=1.[Cl:9][C:10]1[CH:11]=[CH:12][C:13]([F:29])=[C:14]([C:16]2[CH:25]=[C:24](B(O)O)[C:23]3[C:18](=[N:19][CH:20]=[CH:21][CH:22]=3)[N:17]=2)[CH:15]=1.C(=O)([O-])[O-].[Cs+].[Cs+].ClCCl>O1CCOCC1.O.[Pd].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>[Cl:9][C:10]1[CH:11]=[CH:12][C:13]([F:29])=[C:14]([C:16]2[CH:25]=[C:24]([C:5]3[CH:6]=[CH:7][C:2]([NH2:1])=[N:3][CH:4]=3)[C:23]3[C:18](=[N:19][CH:20]=[CH:21][CH:22]=3)[N:17]=2)[CH:15]=1