Water → 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole

HRID 1413107Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1413107
[CH3:1][S:2][C:3]1[NH:7][C:6]2[CH:8]=[C:9]3[C:14](=[CH:15][C:5]=2[N:4]=1)[CH:13]=[CH:12][CH:11]=[CH:10]3.SC[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1.O>C(O)C>[N:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[CH2:1][S:2][C:3]1[NH:4][C:5]2[CH:15]=[C:14]3[C:9](=[CH:8][C:6]=2[N:7]=1)[CH:10]=[CH:11][CH:12]=[CH:13]3

Komponenten

5

Edukt 3

HCID 962WaterHCID 2560712-PyridinemethanethiolHCID 128720792-(methylthio)-1H-naphtho[2,3-d]imidazole

Produkt 1

HCID 223941842-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazoleAusbeute 81,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

0.45 g of 2-methylthio-1H-naphth[2,3-d]imidazole and 0.65 g of 2-mercaptomethylpyridine were heated for 40 hours under reflux in 10 ml of ethanol. 10 ml of water were added to the homogeneous solution and the precipitate formed was filtered off. 0.50 g of 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole having a m.p. of 170° was obtained.

Aufarbeitung

  1. customthe precipitate formed
  2. filtrationwas filtered off

Quellen und Nachweise

ORD-Eintrag
ord-912ef9e4fffc48e484a28a9f07d219fa
Quelldatensatz
uspto-grants-1981_02
Patentnummer
US04248880

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