Hydrochloric Acid → HCID 54124309, Verbindung

HRID 1415220Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1415220
[C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])(=[O:3])[CH3:2].[OH:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH:15]=O.N1CCOCC1.Cl>O.C(O)C>[OH:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH:15]=[CH:2][C:1]([CH:4]1[C:8](=[O:9])[CH2:7][CH2:6][C:5]1=[O:10])=[O:3]

Komponenten

7

Edukt 4

HCID 313Hydrochloric AcidHCID 8083MorpholineHCID 12127IsovanillinHCID 3364732-Acetyl-1,3-cyclopentanedione

Produkt 1

HCID 54124309HCID 54124309, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

2-Acetyl-1,3-cyclopentanedione (3.83 g.) was treated with 5.0 g. of 3-hydroxy-4-methoxybenzaldehyde in 120 ml. of ethanol in the presence of 5 ml. of morpholine under reflux for 5 hours. After cooling, the reaction mixture was poured into 200 ml. of water containing 8 ml. of conc. hydrochloric acid. Deposited crystals were separated by filtration, washed with water and ethanol successively, and dried. 2-(3-Hydroxy-4-methoxycinnamoyl)-1,3-cyclopentanedione (5.46 g.) was obtained, in the form of yellow crystals which showed mp. 137°-139° C. after recrystallisation from a mixed solvent of ethanol and dioxane.

Aufarbeitung

  1. temperatureAfter cooling
  2. additionthe reaction mixture was poured into 200 ml
  3. customDeposited crystals were separated by filtration
  4. washwashed with water and ethanol successively
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-c103825e3ccf495bbd7a3369715b113d
Quelldatensatz
uspto-grants-1977_01
Patentnummer
US04003936

Notizen zur Reaktion

Wird geladen…