Acetic Anhydride → HCID 178526759, Verbindung

HRID 1446104Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1446104
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:11][CH:12]=[CH:13][N+:14]([O-:16])=[O:15])=[C:6]([CH:10]=1)[C:7](O)=[O:8].C([O-])(=O)C.[K+].C(OC(=O)C)(=O)C>>[Br:1][C:2]1[CH:10]=[C:6]2[C:5](=[CH:4][CH:3]=1)[N:11]=[CH:12][C:13]([N+:14]([O-:16])=[O:15])=[C:7]2[OH:8]

Komponenten

4

Edukt 3

HCID 7918Acetic AnhydrideHCID 517044Potassium AcetateHCID 534050555-Bromo-2-(2-nitrovinylamino)benzoic acid

Produkt 1

HCID 178526759HCID 178526759, Verbindung

Versuchsvorschrift

29 g (101 mmol) of 5-bromo-2-(2-nitro-vinylamino)-benzoic acid (Example 1a) and 11.9 g (121 mmol) of potassium acetate in 129 ml (152 mmol) of acetic anhydride are stirred for 1.5 h at 120° C. The precipitate is filtered off and washed with acetic acid until the filtrate is colorless, then is washed with H2O and dried in vacuo to give the title compound. ES-MS: 269, 271 (M+H)+, Br pattern; analytical HPLC: tret=2.70 min (Grad 1).

Aufarbeitung

  1. filtrationThe precipitate is filtered off
  2. washwashed with acetic acid until the filtrate
  3. washis washed with H2O
  4. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-989139a7a5e540ee849b8e0046f0c8da
Quelldatensatz
uspto-grants-2010_02
Patentnummer
US07667039B2

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