Hydrochloric Acid → 5,5-Dioxo-5H-5lambda~6~-thianthrene-3-carboxylic acid

HRID 1447562Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1447562
N[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1Cl)[C:14]([OH:16])=[O:15])(=[O:10])=[O:9].Cl.N([O-])=O.[Na+].O(CC)C([S-])=[S:28].[K+].[OH-].[Na+]>O>[C:14]([C:13]1[CH:17]=[CH:18][C:19]2[S:28][C:2]3[C:3]([S:8](=[O:10])(=[O:9])[C:11]=2[CH:12]=1)=[CH:4][CH:5]=[CH:6][CH:7]=3)([OH:16])=[O:15]

Komponenten

7

Edukt 5

HCID 313Hydrochloric AcidHCID 14798Sodium Hydroxide2×HCID 2735045Potassium ethylxanthateHCID 203841823-(2-Aminobenzene-1-sulfonyl)-4-chlorobenzoic acidHCID 23668193Sodium Nitrite

Produkt 1

HCID 203841685,5-Dioxo-5H-5lambda~6~-thianthrene-3-carboxylic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel3×

Versuchsvorschrift

3-(o-Aminophenylsulphonyl)-4-chlorobenzoic acid (6.00 g) was stirred with concentrated hydrochloric acid (8.0 ml) and water (12.0 ml) and treated at 0°-5° C. with a solution of sodium nitrite (1.50 g) in water (30 ml) over 30 min. After a further 15 min. stirring the suspension was pipetted into a solution of potassium ethyl xanthate (10.2 g) and sodium hydroxide (1.60 g) in water (50 ml) at 45°-50° C. Vigorous nitrogen evolution took place. After the addition was complete the now clear solution was heated to boiling and further sodium hydroxide (3.20 g) was added. Boiling was continued for a further 20 min., and the solution then cooled, filtered and acidified with hydrochloric acid. The solid precipitated acid was filtered off, washed with water, and recrystallised from acetic acid to give 3-carboxythianthrene-5,5-dioxide, m.p. 297°-304° C.; on further recrystallisation from ehtanol it had m.p. 302°-305° C.

Aufarbeitung

  1. additionAfter the addition
  2. temperaturewas heated
  3. waitBoiling was continued for a further 20 min.
  4. temperaturethe solution then cooled
  5. filtrationfiltered
  6. customThe solid precipitated acid
  7. filtrationwas filtered off
  8. washwashed with water
  9. customrecrystallised from acetic acid

Quellen und Nachweise

ORD-Eintrag
ord-6dd64363d9f54019ab0bebea76b6829d
Quelldatensatz
uspto-grants-1979_12
Patentnummer
US04177257

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