Bromine → 5-Bromo-3,3-dimethylbenzofuran-2(3H)-one

HRID 1453039

Reaktionsgleichung

Reaktionsgleichung von HRID 1453039
[CH3:1][C:2]1([CH3:12])[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]1=[O:11].[Br:13]Br>C(O)(=O)C>[Br:13][C:8]1[CH:9]=[CH:10][C:5]2[O:4][C:3](=[O:11])[C:2]([CH3:12])([CH3:1])[C:6]=2[CH:7]=1

Komponenten

4

Edukt 2

HCID 24408BromineHCID 5956202(3H)-Benzofuranone, 3,3-dimethyl-

Produkt 1

HCID 162206345-Bromo-3,3-dimethylbenzofuran-2(3H)-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

3,3-Dimethyl-3H-benzofuran-2-one (2.81 g, 17.3 mmol) was added to a solution of Bromine (1.51 mL, 29.5 mmoL) and Acetic acid (35 mL) at room temperature, then stirred overnight. The resulting mixture was stripped of solvent, then distilled under high vacuum. The product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

Aufarbeitung

  1. distillationdistilled under high vacuum
  2. customThe product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

Quellen und Nachweise

ORD-Eintrag
ord-574d6c0f386d429f874c195961ed76fc
Quelldatensatz
uspto-grants-2009_01
Patentnummer
US07473790B2

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