Morpholine → Morpholine, 4-(2-chloro-4-nitrophenyl)-

HRID 1453653

Reaktionsgleichung

[Cl:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[CH:5]=[CH:6][C:7]=1F.[NH:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>CN(C=O)C>[Cl:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[CH:5]=[CH:6][C:7]=1[N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1

Komponenten

Reaktionsbedingungen

Temperatur: 105 °C

Versuchsvorschrift

1.76 g (10.0 mmol) 3-chloro-4-fluoro-1-nitro-benzene are combined with 2.614 ml (30 mmol) morpholine in 5 ml DMF and heated to 105° C. with stirring for 15 min. The reaction mixture is poured into ice water, the resulting precipitate is suction filtered, washed with water and dried at 50° C. in the drying cupboard.

Aufarbeitung

filtrationfiltered
washwashed with water
customdried at 50° C. in the drying cupboard

Quellen und Nachweise

ORD-Eintrag: ord-45b69a4754604d009d53bf22411bdd7c
Quelldatensatz: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07476663B2

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