1,2-Dichloroethane → 3(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)benzylamino)acetylamino)-4-(4-(2,6-dichlorophenyl)-oxazol-2-yl)-4-hydroxybutyric Acid tert-Butyl Ester

Reaktionsgleichung

[C:1]([NH:9][C@@H:10]([CH:25]([CH3:27])[CH3:26])[C:11]([N:13]([CH2:21][C:22](O)=[O:23])[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:28]([O:32][C:33](=[O:58])[CH:34](N)[C@H:35](C(OCC=C)=O)[CH:36]([C:38]1[O:39][CH:40]=[C:41]([C:43]2[C:48]([Cl:49])=[CH:47][CH:46]=[CH:45][C:44]=2[Cl:50])[N:42]=1)[OH:37])([CH3:31])([CH3:30])[CH3:29].C([SnH](CCCC)CCCC)CCC.C1C=CC2N(O)N=[N:78]C=2C=1.C(Cl)CCl>[Pd](Cl)Cl.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.CN(C=O)C.C(Cl)Cl>[C:28]([O:32][C:33](=[O:58])[CH2:34][C@H:35]([NH:78][C:22](=[O:23])[CH2:21][N:13]([C:11](=[O:12])[C@@H:10]([NH:9][C:1](=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)[CH:25]([CH3:27])[CH3:26])[CH2:14][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)[CH:36]([C:38]1[O:39][CH:40]=[C:41]([C:43]2[C:48]([Cl:49])=[CH:47][CH:46]=[CH:45][C:44]=2[Cl:50])[N:42]=1)[OH:37])([CH3:31])([CH3:30])[CH3:29]