Pyridoxal hydrochloride → Pyridoxal

HRID 1486476

Reaktionsgleichung

Reaktionsgleichung von HRID 1486476
[CH3:1][C:2]1[C:7]([OH:8])=[C:6]([CH:9]=[O:10])[C:5]([CH2:11][OH:12])=[CH:4][N:3]=1.Cl.C(=O)(O)[O-].[Na+]>O>[CH3:1][C:2]1[N:3]=[CH:4][C:5]([CH2:11][OH:12])=[C:6]([CH:9]=[O:10])[C:7]=1[OH:8]

Komponenten

4

Edukt 2

HCID 6171Pyridoxal hydrochlorideHCID 516892Sodium Bicarbonate

Produkt 1

HCID 1050PyridoxalAusbeute 81,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

1.016 g (5 mmol) of pyridoxal hydrochloride (Aldrich) was placed in an Erlenmeyer and a solution of 0.456 g sodium bicarbonate (5.4 mmol) in 5 mL water was added. The resulting solution was set aside for some time and crystals precipitated. The thus precipitated crystals were collected by filtration, washed with cold water and dried to afford 0.68 g of the pyridoxal free base (80% yield).

Aufarbeitung

  1. customprecipitated
  2. filtrationThe thus precipitated crystals were collected by filtration
  3. washwashed with cold water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-5f302a90dd0744fbba641e2dbf36b42c
Quelldatensatz
uspto-grants-2016_08
Patentnummer
US09428458B2

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