Butylamine → 4-Butylamino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine

HRID 1493407

Reaktionsgleichung

Reaktionsgleichung von HRID 1493407
[CH:1]1([O:7][N:8]2[C:13]([CH3:15])([CH3:14])[CH2:12][C:11](=O)[CH2:10][C:9]2([CH3:18])[CH3:17])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:19]([NH2:23])[CH2:20][CH2:21][CH3:22].[H][H]>[Pt]=O.C(O)C>[CH2:19]([NH:23][CH:11]1[CH2:12][C:13]([CH3:15])([CH3:14])[N:8]([O:7][CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[C:9]([CH3:18])([CH3:17])[CH2:10]1)[CH2:20][CH2:21][CH3:22]

Komponenten

6

Edukt 3

HCID 8007ButylamineHCID 22019868N-cyclohexyloxy-4-oxo-2,2,6,6-tetramethylpiperidineHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 211821294-Butylamino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidineAusbeute 93 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 9.5 grams (37.5 mmol) of 1-cyclohexyloxy-2, 2,6,6-tetramethylpiperidin-4-one, 13.7 grams (187 mmol) of n-butylamine, 0.4 gram of platinum oxide, and 120 ml of ethanol is hydrogenated on a Parr apparatus (50 psi, ambient temperature) till hydrogen uptake ceases. The catalyst is removed by filtration and the filtrate is evaporated to afford 10.8 grams (93% yield) of the title compound as a colorless syrup.

Aufarbeitung

  1. customThe catalyst is removed by filtration
  2. customthe filtrate is evaporated

Quellen und Nachweise

ORD-Eintrag
ord-92bc46701d1a47ceb4a90b541d5d45f2
Quelldatensatz
uspto-grants-1991_06
Patentnummer
US05021481

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