Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester → Hydroxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester

HRID 1518174

Reaktionsgleichung

Reaktionsgleichung von HRID 1518174
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][C:21]2[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][C:22]=2[Cl:28])=[C:6]([O:8][C:9](=[O:19])[CH2:10][O:11]CC2C=CC=CC=2)[CH:7]=1>CO.[Pd]>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][C:21]2[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][C:22]=2[Cl:28])=[C:6]([O:8][C:9](=[O:19])[CH2:10][OH:11])[CH:7]=1

Komponenten

4

Edukt 1

HCID 57667396Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester

Produkt 1

HCID 57667367Hydroxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester 4 (5 grams) was dissolved in methanol (50 mL) in a pressure vessel, palladium on carbon (5%, 5 grams) was added and the mixture was stirred under an atmosphere of hydrogen (4 Kg) for 4 hours. The catalyst was removed by filtration and the methanol was distilled off to yield crude 5.

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. distillationthe methanol was distilled off
  3. customto yield crude 5

Quellen und Nachweise

ORD-Eintrag
ord-3a5c37b98057400886749780a484c000
Quelldatensatz
uspto-grants-2012_07
Patentnummer
US08232422B2

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