Magnesium Stearate → Clonidine

HRID 1527648

Reaktionsgleichung

Reaktionsgleichung von HRID 1527648
[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([NH:8][C:9]2[NH:13][CH2:12][CH2:11][N:10]=2)=[C:3]([Cl:14])[CH:2]=1.Cl.OP([O-])([O-])=O.[Ca+2].C([O-])(=O)CCCCCCCCCCCCCCCCC.[Mg+2].C([O-])(=O)CCCCCCCCCCCCCCCCC>>[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([NH:8][C:9]2[NH:13][CH2:12][CH2:11][N:10]=2)=[C:3]([Cl:14])[CH:2]=1

Komponenten

4

Edukt 3

HCID 11177Magnesium StearateHCID 20179Clonidine HydrochlorideHCID 24441Calcium hydrogen phosphate

Produkt 1

HCID 2803Clonidine

Versuchsvorschrift

Basically 0.1 mg (base equivalent) of clonidine hydrochloride was blended with 13 mg of calcium phosphate dibasic, with 15 mg of microcrystalline cellulose, with 40 mg of hydroxypropyl methyl cellulose, 1 mg of colloidal silica and 0.9 mg of magnesium stearate.

Quellen und Nachweise

ORD-Eintrag
ord-d5c273cad9c4439f94bde23bc6e97369
Quelldatensatz
uspto-grants-2015_07
Patentnummer
US09089559B2

Verknüpfte Notizen

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