1-(4-Ethylaminophenyl)-4-phenylmethylpiperazine → 1-(4-Ethylaminophenyl)piperazine

HRID 1533907

Reaktionsgleichung

Reaktionsgleichung von HRID 1533907
[CH2:1]([NH:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][N:13](CC3C=CC=CC=3)[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)[CH3:2]>C(O)C.[Pd]>[CH2:1]([NH:3][C:4]1[CH:5]=[CH:6][C:7]([N:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)=[CH:8][CH:9]=1)[CH3:2]

Komponenten

4

Edukt 1

HCID 199114651-(4-Ethylaminophenyl)-4-phenylmethylpiperazine

Produkt 1

HCID 199114581-(4-Ethylaminophenyl)piperazine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 1-(4-ethylaminophenyl)-4-phenylmethylpiperazine in ethanol is catalytically hydrogenated at about 70° C. and 50 p.s.i., in the presence of 10% palladium on carbon. After hydrogen uptake ceases, the catalyst is removed by filtration and the filtrate concentrated to obtain the title compound.

Aufarbeitung

  1. customis catalytically hydrogenated at about 70° C.
  2. customAfter hydrogen uptake ceases, the catalyst is removed by filtration
  3. concentrationthe filtrate concentrated

Quellen und Nachweise

ORD-Eintrag
ord-590c27b31dff476298179a48dbf18bb1
Quelldatensatz
uspto-grants-1992_02
Patentnummer
US05086055

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