Hydrochloric Acid → N-{5-[(2-{[(2,2-dimethylcyclopropyl)carbonyl]amino}imidazo[1,2-b]pyridazin-6-yl)oxy]-2-fluorophenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

HRID 1556696

Reaktionsgleichung

Reaktionsgleichung von HRID 1556696
[CH3:1][C:2]1([CH3:8])[CH:3]([C:5](=[O:6])[OH:7])[CH2:4]1.[CH3:49][N:50]([CH3:51])[C:52](=[O:53])[CH3:54].[CH3:9][N:10]([CH3:11])[CH:12]=[O:13].[Cl:14][C:15]([C:16]([Cl:17])=[O:18])=[O:19].[ClH:20].[NH2:21][c:22]1[n:23][c:24]2[n:25]([n:26][c:27]([O:30][c:31]3[cH:32][cH:33][c:34]([F:47])[c:35]([NH:37][C:38](=[O:39])[c:40]4[cH:41][c:42]([CH3:46])[n:43][n:44]4[CH3:45])[cH:36]3)[cH:28][cH:29]2)[cH:48]1.[O:55]1[CH2:56][CH2:57][CH2:58][CH2:59]1>>[CH3:1][C:2]1([CH3:8])[CH:3]([C:5](=[O:6])[NH:21][c:22]2[n:23][c:24]3[n:25]([n:26][c:27]([O:30][c:31]4[cH:32][cH:33][c:34]([F:47])[c:35]([NH:37][C:38](=[O:39])[c:40]5[cH:41][c:42]([CH3:46])[n:43][n:44]5[CH3:45])[cH:36]4)[cH:28][cH:29]3)[cH:48]2)[CH2:4]1

Komponenten

8

Edukt 7

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 31374DimethylacetamideHCID 65578Oxalyl chlorideHCID 2607082,2-Dimethylcyclopropane-1-carboxylic acidHCID 57505568N-[5-(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy-2-fluorophenyl]-2,5-dimethylpyrazole-3-carboxamide

Produkt 1

HCID 57505605N-{5-[(2-{[(2,2-dimethylcyclopropyl)carbonyl]amino}imidazo[1,2-b]pyridazin-6-yl)oxy]-2-fluorophenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

Quellen und Nachweise

ORD-Eintrag
ord-f1b6398bcc4f43b1a5d16d273bcfa403
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

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