Phenyl isocyanate → 1-Ethyl-3-(phenylcarbamoyl)urea

HRID 1577136

Reaktionsgleichung

Reaktionsgleichung von HRID 1577136
[CH2:1]([NH:3][C:4]([NH2:6])=[O:5])[CH3:2].[C:7]1([N:13]=[C:14]=[O:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>O1CCOCC1>[CH2:1]([NH:3][C:4]([NH:6][C:14]([NH:13][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:15])=[O:5])[CH3:2]

Komponenten

4

Edukt 2

HCID 7672Phenyl isocyanateHCID 12254Ethylurea

Produkt 1

HCID 128764091-Ethyl-3-(phenylcarbamoyl)ureaAusbeute 55,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

In 50 ml of anhydrous dioxane, 3.5 g (0.04 mol) of ethyl urea was dissolved, and under stirring 4.8 g (0.04 mol) of phenylisocyanate was added thereinto. The reaction was carried out at a room temperature for 15 hours, then the solvent was removed by distillation under a reduced pressure. The residue thus obtained was recrystallized from ethanol-water to obtain 4.6 g (yield 55%) of 1-ethyl-5-phenylbiuret having a melting point of 80°-81.5° C.

Aufarbeitung

  1. additionwas added
  2. customthe solvent was removed by distillation under a reduced pressure
  3. customThe residue thus obtained
  4. customwas recrystallized from ethanol-water

Quellen und Nachweise

ORD-Eintrag
ord-a0e669e731694cf3af47b31266aac5aa
Quelldatensatz
uspto-grants-1981_09
Patentnummer
US04287207

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