Carbon Tetrachloride → Ethyl 3-bromo-6-methoxy-2-methylbenzoate

HRID 1586587

Reaktionsgleichung

Reaktionsgleichung von HRID 1586587
[CH3:1][C:2]1[C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][CH:3]=1.[Br:15]Br.ClC(Cl)(Cl)Cl>O>[Br:15][C:3]1[CH:4]=[CH:5][C:6]([O:13][CH3:14])=[C:7]([C:2]=1[CH3:1])[C:8]([O:10][CH2:11][CH3:12])=[O:9]

Komponenten

5

Edukt 3

HCID 5943Carbon TetrachlorideHCID 24408BromineHCID 5910602-Methoxy-6-methyl-benzoic acid ethyl ester

Produkt 1

HCID 11022052Ethyl 3-bromo-6-methoxy-2-methylbenzoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of ethyl 6-methyl-2-methoxybenzoate (8.4 g, 43.2 mmol), bromine (6.9 g, 43.2 mmol) and tetrachloromethane (170 ml) is stirred at room temperature for 60 hours. The reaction mixture is poured into water and extracted with ethyl acetate. The organic phase is separated and concentrated. The crude product is obtained as a yellow oil, 10.3 g (87% y) and is used without further purification.

Aufarbeitung

  1. extractionextracted with ethyl acetate
  2. customThe organic phase is separated
  3. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-764df8cc1a0c436faa7522f56ba7521e
Quelldatensatz
uspto-grants-1999_08
Patentnummer
US05945567

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