Bromine → 2-Bromo-7-nitro-3,4-dihydronaphthalen-1(2H)-one

HRID 1586710Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1586710
[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][C:11]2=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Br:15]Br>CCOCC>[Br:15][CH:10]1[CH2:9][CH2:8][C:7]2[C:12](=[CH:13][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)[C:11]1=[O:14]

Komponenten

4

Edukt 2

HCID 24408BromineHCID 384457-Nitro-1-tetralone

Produkt 1

HCID 131941302-Bromo-7-nitro-3,4-dihydronaphthalen-1(2H)-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

To a suspension of 9.56 g (0.05 mol) of 7-nitro-1-tetralone in 250 mL of ether was added bromine dropwise. The progress of the reaction was followed by thin layer chromatography (fl. silica gel/CH2Cl2). When all of the starting material had been consumed, the mixture was concentrated and cyclohexane was added. The white solid was removed by filtration to afford 2.25 g of 2-bromo-7-nitrotetralone, mp 94°-96° C.

Aufarbeitung

  1. customWhen all of the starting material had been consumed
  2. concentrationthe mixture was concentrated
  3. additioncyclohexane was added
  4. customThe white solid was removed by filtration

Quellen und Nachweise

ORD-Eintrag
ord-26043992f42145718bf92943cdc23514
Quelldatensatz
uspto-grants-1993_06
Patentnummer
US05215989

Notizen zur Reaktion

Wird geladen…