Stattic → 6-Amino-2,3-dihydro-1lambda6-benzothiophene-1,1-dione

HRID 1593027Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1593027
[N+:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH:8]=[CH:9][S:10](=[O:12])(=[O:11])[C:6]=2[CH:5]=1)([O-])=O>C(O)(=O)C.C(OCC)(=O)C.[Pd]>[S:10]1(=[O:11])(=[O:12])[C:6]2[CH:5]=[C:4]([NH2:1])[CH:14]=[CH:13][C:7]=2[CH2:8][CH2:9]1

Komponenten

5

Edukt 1

HCID 2779853Stattic

Produkt 1

HCID 122853256-Amino-2,3-dihydro-1lambda6-benzothiophene-1,1-dioneAusbeute 121,9 %

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 23938PalladiumKatalysatorHCID 176Acetic AcidLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

A solution of 6-nitro-1-benzothiophene 1,1-dioxide (1.04 g) in acetic acid (50 ml) and ethyl acetate (50 ml) was hydrogenated over (10% palladium on carbon (130 mg, 50% wet). The catalyst was removed by filtration and washed with ethyl acetate. The filtrate and washings were evaporated under reduced pressure to give the title compound (1.1 g). LCMS RT=1.50 min

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. washwashed with ethyl acetate
  3. customThe filtrate and washings were evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-06bafa995bcd4514b6ac26f4e65360e1
Quelldatensatz
uspto-grants-2007_11
Patentnummer
US07294650B2

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