Water → HCID 10126767, Verbindung

HRID 1595211Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1595211
[Mn]([O-])(=O)(=O)=[O:2].[K+].[CH3:7][O:8][C:9]1[CH:10]=[C:11]2[O:32][C:31]([CH3:34])([CH3:33])[CH:30]=[CH:29][C:12]2=[C:13]2[C:22]=1[C:21](=[O:23])[C:20]1[CH:19]=[C:18]3[CH:24]=[CH:25][CH:26]=[CH:27][C:17]3=[CH:16][C:15]=1[N:14]2[CH3:28].[OH2:35]>CC(C)=O>[O:35]=[C:29]1[C:12]2=[C:13]3[C:22](=[C:9]([O:8][CH3:7])[CH:10]=[C:11]2[O:32][C:31]([CH3:34])([CH3:33])[CH:30]1[OH:2])[C:21](=[O:23])[C:20]1[CH:19]=[C:18]2[CH:24]=[CH:25][CH:26]=[CH:27][C:17]2=[CH:16][C:15]=1[N:14]3[CH3:28]

Komponenten

5

Edukt 3

HCID 962WaterHCID 516875Potassium PermanganateHCID 9799569HCID 9799569, Verbindung

Produkt 1

HCID 10126767HCID 10126767, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

A solution of 8.1 g of potassium permanganate diluted in 30 ml of water is slowly added at room temperature to a solution of 3.5 g of the product of Example 2 in 50 ml of acetone. After 2 hours, the solution is concentrated under reduced pressure. The residue is then mixed with silica and then chromatographed on silica gel (dichloromethane/methanol: 98/2), allowing the compound of Example 4, which is present in a small amount, to be isolated from the expected product.

Aufarbeitung

  1. concentrationthe solution is concentrated under reduced pressure
  2. additionThe residue is then mixed with silica
  3. customchromatographed on silica gel (dichloromethane/methanol: 98/2)

Quellen und Nachweise

ORD-Eintrag
ord-09ee8fe9a13c4dd7afeec0bb2349df8b
Quelldatensatz
uspto-grants-2001_09
Patentnummer
US06288073B1

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