Isopropanol → 2-tert-Butylcyclohexyloxybutanol

HRID 1613542

Reaktionsgleichung

Reaktionsgleichung von HRID 1613542
[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[O:11][CH2:12][CH:13]([OH:16])[CH2:14][CH3:15])([CH3:4])([CH3:3])[CH3:2].C(O)(C)C.[H][H]>[Pd].O>[C:1]([CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH:6]1[O:11][CH2:12][CH:13]([OH:16])[CH2:14][CH3:15])([CH3:4])([CH3:3])[CH3:2]

Komponenten

6

Edukt 3

HCID 3776IsopropanolHCID 197740621-(2-tert-Butylphenoxy)butan-2-olHCID 178418361HCID 178418361, Verbindung2×

Produkt 1

HCID 1644222-tert-ButylcyclohexyloxybutanolAusbeute 73,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 962WaterLösungsmittel

Versuchsvorschrift

To a 500 ml autoclave, 50 g (0.23 mol) of 1-(2-tertbutylphenyloxy)-2-butanol, 150 g of isopropanol and 1.0 g of 5 weight % palladium catalyst supported on active carbon containing 50 weight % water (produced by N. E. Chemcat Co.) were added, and the mixture obtained was reacted at 190° C. at a hydrogen pressure of 70 kg/cm2 for 27 hours until absorption of hydrogen had stopped. After the reaction was finished, the catalyst was filtered to remove it, and the reacted solution was distilled and 38.8 g of 1-(2-tert-butylcyclohexyloxy)-2-butanol (cis:trans=63:37) were obtained in a 74% yield of product.

Aufarbeitung

  1. additionwere added
  2. customthe mixture obtained
  3. filtrationthe catalyst was filtered
  4. customto remove it
  5. distillationthe reacted solution was distilled

Quellen und Nachweise

ORD-Eintrag
ord-1761df277640423dbff407ebff739ff3
Quelldatensatz
uspto-grants-1993_03
Patentnummer
US05194423

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