Phenacyl bromide → Phenacyl thiocyanate

HRID 1660671Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1660671
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4].[SiH4].[S-:12][C:13]#[N:14].[Na+]>C(O)C>[S:12]([CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4])[C:13]#[N:14]

Komponenten

5

Edukt 3

HCID 6259Phenacyl bromideHCID 23953SilaneHCID 516871Sodium thiocyanate

Produkt 1

HCID 219693Phenacyl thiocyanate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Bromoacetophenone-modified aminopropylsilylated glass surfaces (2.5×7.5 cm; Sigma, Silane-Prep™, S4651) (see Example 13) were coated with a 0.1M solution of sodium thiocyanate in ethanol and incubated for five hours at 50° C. The glass surfaces thus treated were then washed five times using respectively 30 mL of ethanol for 3 minutes each at room temperature. After washing three times for three minutes each using respectively 30 mL of DCM at room temperature, the glass surfaces were dried and stored at 4° C. until further use.

Aufarbeitung

  1. additionThe glass surfaces thus treated
  2. washwere then washed five times
  3. customfor 3 minutes
  4. customat room temperature
  5. washAfter washing three times for three minutes each using respectively 30 mL of DCM at room temperature
  6. customthe glass surfaces were dried
  7. customstored at 4° C. until further use

Quellen und Nachweise

ORD-Eintrag
ord-6c69b8cd2f5d46608e9d805dbc1a368d
Quelldatensatz
uspto-grants-2011_10
Patentnummer
US08029979B2

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