Hydrochloric Acid → (2S,4S)-1-(tert-butoxycarbonyl)-4-(8-chloro-7-methoxy-2-(3-(trifluoromethyl)-1H-pyrazol-1-yl)quinolin-4-yloxy)pyrrolidine-2-carboxylic acid

Reaktionsgleichung

[Cl:1][C:2]1[C:3]([O:38][CH3:39])=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([N:12]1[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[N:13]1)[CH:8]=[C:7]2[O:21][C@@H:22]1[CH2:26][N:25]([C:27]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:28])[C@H:24]([C:34]([O:36]C)=[O:35])[CH2:23]1.[Li+].[OH-].O.Cl>C1COCC1>[C:30]([O:29][C:27]([N:25]1[CH2:26][C@@H:22]([O:21][C:7]2[C:6]3[C:11](=[C:2]([Cl:1])[C:3]([O:38][CH3:39])=[CH:4][CH:5]=3)[N:10]=[C:9]([N:12]3[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:18])[F:19])=[N:13]3)[CH:8]=2)[CH2:23][C@H:24]1[C:34]([OH:36])=[O:35])=[O:28])([CH3:33])([CH3:31])[CH3:32]