2-Phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamate → 2-Hydroxy-1-(hydroxymethyl)ethyl 4-(hexadecylamino)hydrocinnamate

HRID 1702685Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1702685
[CH2:1]([NH:17][C:18]1[CH:40]=[CH:39][C:21]([CH2:22][CH2:23][C:24]([O:26][CH:27]2[CH2:32][O:31]C(C3C=CC=CC=3)[O:29][CH2:28]2)=[O:25])=[CH:20][CH:19]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[H][H]>[Pd].C(O)(=O)C>[CH2:1]([NH:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:22][CH2:23][C:24]([O:26][CH:27]([CH2:28][OH:29])[CH2:32][OH:31])=[O:25])=[CH:39][CH:40]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Komponenten

5

Edukt 2

HCID 536327232-Phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamateHCID 178418361HCID 178418361, Verbindung2×

Produkt 1

HCID 540874802-Hydroxy-1-(hydroxymethyl)ethyl 4-(hexadecylamino)hydrocinnamate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

A mixture of 2-phenyl-1,3-dioxan-5-yl 4-(hexadecylamino)hydrocinnamate, 10% palladium-on-carbon and acetic acid is treated with hydrogen in a Parr apparatus at room temperature until hydrogen uptake ceases. The mixture is filtered and the filtrate is evaporated. Recrystallization of the residue from chloroform provides the title compound.

Aufarbeitung

  1. filtrationThe mixture is filtered
  2. customthe filtrate is evaporated
  3. customRecrystallization of the residue from chloroform

Quellen und Nachweise

ORD-Eintrag
ord-725f4360b40c430493054031178b1f00
Quelldatensatz
uspto-grants-1982_09
Patentnummer
US04348399

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