Water → 4,5,5-Trifluoro-4-penten-1-ol

HRID 1710014Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1710014
[H-].[Al+3].[Li+].[H-].[H-].[H-].[F:7][C:8](=[C:14]([F:16])[F:15])[CH2:9][CH2:10][C:11](O)=[O:12].O>C(OCC)C>[F:7][C:8](=[C:14]([F:16])[F:15])[CH2:9][CH2:10][CH2:11][OH:12]

Komponenten

5

Edukt 3

HCID 962WaterHCID 27824474,5,5-trifluoropent-4-enoic AcidHCID 21226445Aluminium lithium hydride

Produkt 1

HCID 27779334,5,5-Trifluoro-4-penten-1-olAusbeute 57,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel2×

Versuchsvorschrift

To a stirred suspension of 0.4 gram (0.01 mole) of lithium aluminum hydride in 20 ml of diethyl ether was added dropwise a solution of 1.5 grams (0.01 mole) of 4,5,5-trifluoro-4-pentenoic acid in 30 ml of diethyl ether. Upon completion of addition the reaction mixture was stirred at ambient temperature for one hour, then 20 ml of water was added carefully. The mixture was filtered and the filtrate concentrated under reduced pressure to give 0.8 gram of 4,5,5-trifluoro-4-penten-1-ol as an oil. The nmr and the ir spectra were consistent with the proposed structure.

Aufarbeitung

  1. additionUpon completion of addition the reaction mixture
  2. filtrationThe mixture was filtered
  3. concentrationthe filtrate concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-55f5c6633b8841daaa2ef5f0a3761a9c
Quelldatensatz
uspto-grants-1990_08
Patentnummer
US04952580

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