Methane → 5-Methoxynaphthalen-1-amine

HRID 1719863Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1719863
O.NN.[CH3:4][O:5][C:6]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:7]=1[CH:8]=[CH:9][CH:10]=[C:11]2[N+:16]([O-])=O.C.NN>C(O)C>[NH2:16][C:11]1[C:12]2[C:7](=[C:6]([O:5][CH3:4])[CH:15]=[CH:14][CH:13]=2)[CH:8]=[CH:9][CH:10]=1

Komponenten

6

Edukt 4

HCID 297Methane2×HCID 9321HydrazineHCID 24654Hydrazine hydrate (1:1)HCID 127385811-Methoxy-5-nitronaphthalene

Produkt 1

HCID 2355485-Methoxynaphthalen-1-amine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

Hydrazine hydrate (150 ml) is added slowly to a stirred mixture of 5-methoxy-1-nitro-naphthalene (320 g), and palladized charcoal (0.1 g) in 95% ethanol (2 liters) previously warmed to 50° C. When the hydrazine addition is complete, additional palladized charcoal (0.1 g) is added and the mixture heated to reflux for about one hour. The reaction mixture is filtered through Celite and the filtrate evaporated in vacuo resulting in a white solid which is recrystallized from H2O and ethanol.

Aufarbeitung

  1. temperaturethe mixture heated
  2. temperatureto reflux for about one hour
  3. filtrationThe reaction mixture is filtered through Celite
  4. customthe filtrate evaporated in vacuo
  5. customresulting in a white solid which
  6. customis recrystallized from H2O and ethanol

Quellen und Nachweise

ORD-Eintrag
ord-e95988124cf644d59d2bc3b9b51a4a22
Quelldatensatz
uspto-grants-1985_09
Patentnummer
US04543352

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