Water → HCID 13051147, Verbindung
Reaktionsgleichung
[O:1]=[C:2]1[N:9]2[CH:4]([CH2:5][CH2:6][O:7]C2(C)C)[CH:3]1[CH:12]([CH3:14])[CH3:13].O>C(O)(=O)C>[CH:12]([CH:3]1[CH:4]([CH2:5][CH2:6][OH:7])[NH:9][C:2]1=[O:1])([CH3:14])[CH3:13]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 65 °C
Versuchsvorschrift
8-oxo-2,2-dimethyl-7α-isopropyl-3-oxa-1-azabicyclo[4.2.0]octane 1.0 g is dissolved in 8 ml of acetic acid and 2 ml H2O is added. The mixture is heated at 65° C. for 1.25 hrs. The acetic acid and H2O are removed under reduced pressure and the residue is taken up in C6H6 and evaporated to give 3-isopropyl-4-(2-hydroxyethyl)azetidinone.
Aufarbeitung
- customThe acetic acid and H2O are removed under reduced pressure
- customevaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-606197c8eaaa413ebb2146b94048287f
- Quelldatensatz
- uspto-grants-1985_09
- Patentnummer
- US04543257
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