Water → HCID 70467484, Verbindung

HRID 1731871Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1731871
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[CH:6]=O.C([CH:16](C([NH:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25]C=1)=O)[C:17]([OH:19])=[O:18])(O)=O.[NH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1.[OH2:35].[C:36]1([CH3:42])C=CC=CC=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[CH:6]=[CH:42][C:36]([NH:29][C:34]1[C:16](=[CH:30][CH:31]=[CH:32][CH:33]=1)[C:17]([O-:19])=[O:18])=[O:35].[NH2+:22]1[CH2:23][CH2:28][CH2:27][CH2:26][CH2:25]1

Komponenten

6

Edukt 5

HCID 962WaterHCID 1140TolueneHCID 8082PiperidineHCID 8419VeratraldehydeHCID 20222317HCID 20222317, Verbindung

Produkt 1

HCID 70467484HCID 70467484, VerbindungAusbeute 94,8 %

Versuchsvorschrift

A solution of 8.4 g of 3,4-dimethoxybenzaldehyde, 11.4 g of 2-carboxymalonanilic acid, and 4.3 g of piperidine in 50 ml of toluene is heated for 3 hours under reflux with continuous removal of water during the reaction period. After the completion of the reaction, the reaction mixture is cooled and the precipitated crystals are collected by filtration and dried to obtain 19.5 g of piperidinium N-(3,4-dimethoxycinnamoyl)anthranilate (94.8% yield), as confirmed by elemental analysis and spectroscopy.

Aufarbeitung

  1. customAfter the completion of the reaction
  2. temperaturethe reaction mixture is cooled
  3. filtrationthe precipitated crystals are collected by filtration
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-756942962bbd4a399ecf5348ee63efd9
Quelldatensatz
uspto-grants-1986_11
Patentnummer
US04623724

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