Triethylamine → n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide

HRID 1738993

Reaktionsgleichung

Reaktionsgleichung von HRID 1738993
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][S:11]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)(=[O:13])=[O:12])=[CH:6][CH:5]=1)([O-])=O.[CH2:21]([Mg]Cl)[CH:22]([CH3:24])[CH3:23].[Br:27]Br.C([N:31](CC)CC)C>C1COCC1.CCOCC>[BrH:27].[NH:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][S:11]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)(=[O:13])=[O:12])=[CH:6][C:5]=1[CH2:21][CH:22]([CH3:24])[CH3:23])[NH2:31]

Komponenten

7

Edukt 4

HCID 8471TriethylamineHCID 24408BromineHCID 69772Benzenesulfonamide, 4-methyl-N-(4-nitrophenyl)-HCID 178418368HCID 178418368, Verbindung

Produkt 1

HCID 22111802n-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

This compound is prepared according to the procedure described in step A of Preparation 2.18, from 10 g of N-(4-nitrophenyl)-4-methylbenzenesulphonamide in 100 ml of THF and 42.6 ml of a 2M solution of isobutylmagnesium chloride in ether, followed by 4.4 ml of bromine and 23.4 ml of triethylamine. 5.9 g of the expected product are obtained, m.p.=170° C.

Aufarbeitung

  1. customThis compound is prepared

Quellen und Nachweise

ORD-Eintrag
ord-b4a2a704465c4967897c215155437146
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05965579

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