Water → HCID 10499321, Verbindung

HRID 1740637Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1740637
Cl[C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1.O.O.[NH2:29][NH2:30]>>[NH:29]([C:2]1[CH:7]=[C:6]([C:8]2[C:17]3[C:12](=[CH:13][C:14]([O:21][CH3:22])=[C:15]([O:18][CH2:19][CH3:20])[CH:16]=3)[CH:11]=[C:10]([CH2:23][OH:24])[C:9]=2[CH2:25][OH:26])[CH:5]=[CH:4][N:3]=1)[NH2:30]

Komponenten

4

Edukt 3

HCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 10738129HCID 10738129, Verbindung

Produkt 1

HCID 10499321HCID 10499321, Verbindung

Versuchsvorschrift

A suspension of 1-(2-chloro-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (16.0 g) in hydrazine hydrate (50 ml) is refluxed for four hours. The mixture is cooled to room temperature, and then thereto is added water. The precipitated crystals are collected by filtration, washed with water, and dried to give 1-(2-hydrazino-4-pyridyl)-2,3-bis(hydroxymethyl)-6-methoxy-7-ethoxynaphthalene (14.5 g).

Aufarbeitung

  1. temperatureis refluxed for four hours
  2. filtrationThe precipitated crystals are collected by filtration
  3. washwashed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-26dc8cd3b7334b98a9bb93209f8697d0
Quelldatensatz
uspto-grants-1999_10
Patentnummer
US05969140

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