2,3-Dihydroxybutanedioic Acid → 2-Methyl-2-(2-methyl-5-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole-5-carbonyl]-piperidin-3-yl}-phenoxy)-propionic acid ethyl ester

HRID 174210

Reaktionsgleichung

Reaktionsgleichung von HRID 174210
[C:1]([OH:2])(=[O:3])[CH:4]([CH:5]([C:6]([OH:7])=[O:8])[OH:9])[OH:10].[CH2:11]([CH3:12])[O:13][C:14]([C:15]([CH3:16])([O:17][c:18]1[c:19]([CH3:30])[cH:20][cH:21][c:22]([CH:24]2[CH2:25][NH:26][CH2:27][CH2:28][CH2:29]2)[cH:23]1)[CH3:31])=[O:32].[CH3:33][N:34]([CH3:35])[CH2:36][CH2:37][CH2:38][N:39]=[C:40]=[N:41][CH2:42][CH3:43].[CH3:44][c:45]1[n:46][c:47](-[c:53]2[cH:54][cH:55][c:56]([C:59]([F:60])([F:61])[F:62])[cH:57][cH:58]2)[s:48][c:49]1[C:50](=[O:51])[OH:52].[CH3:63][CH2:64][O:65][C:66](=[O:67])[CH3:68].[CH3:69][CH2:70][O:71][CH2:72][CH3:73]>>[CH2:11]([CH3:12])[O:13][C:14]([C:15]([CH3:16])([O:17][c:18]1[c:19]([CH3:30])[cH:20][cH:21][c:22]([CH:24]2[CH2:25][N:26]([C:50]([c:49]3[c:45]([CH3:44])[n:46][c:47](-[c:53]4[cH:54][cH:55][c:56]([C:59]([F:60])([F:61])[F:62])[cH:57][cH:58]4)[s:48]3)=[O:51])[CH2:27][CH2:28][CH2:29]2)[cH:23]1)[CH3:31])=[O:32]

Komponenten

7

Edukt 6

HCID 8752,3-Dihydroxybutanedioic AcidHCID 3283Diethyl EtherHCID 8857Ethyl AcetateHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 27756634-Methyl-2-(4-(trifluoromethyl)phenyl)-5-thiazolecarboxylic acidHCID 68883087Ethyl 2-methyl-2-(2-methyl-5-piperidin-3-ylphenoxy)propanoate

Produkt 1

HCID 688866962-Methyl-2-(2-methyl-5-{1-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole-5-carbonyl]-piperidin-3-yl}-phenoxy)-propionic acid ethyl ester

Quellen und Nachweise

ORD-Eintrag
ord-c155cd05a6fa40358037894363c01947
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Verknüpfte Notizen

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