Acetic Anhydride → HCID 22238064, Verbindung

HRID 1743385Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1743385
[C:1](OC(=O)C)(=[O:3])C.[CH3:8][CH:9]1[CH2:17][C:16]2[C:11](=[C:12]([CH3:20])[C:13]([CH3:19])=[C:14]([OH:18])[CH:15]=2)[NH:10]1>C(O)=O>[OH:18][C:14]1[CH:15]=[C:16]2[C:11](=[C:12]([CH3:20])[C:13]=1[CH3:19])[N:10]([CH:1]=[O:3])[CH:9]([CH3:8])[CH2:17]2

Komponenten

4

Edukt 2

HCID 7918Acetic AnhydrideHCID 22238098HCID 22238098, Verbindung

Produkt 1

HCID 22238064HCID 22238064, VerbindungAusbeute 49 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 284Formic AcidLösungsmittel

Versuchsvorschrift

Acetic anhydride (0.76 mL, 8.1 mmol) was added to formic acid (4 mL), and the mixture was stirred at room temperature for 15 minutes. To this solution was added 2,3-dihydro-2,6,7-trimethyl-1H-indole-5-ol (0.71 g, 4.0 mmol), and the mixture was stirred at room temperature for 5 hours. Ice was added to the reaction mixture, and precipitated solid was filtered to obtain 0.40 g of the title compound.

Aufarbeitung

  1. stirringthe mixture was stirred at room temperature for 5 hours
  2. additionIce was added to the reaction mixture
  3. customprecipitated solid
  4. filtrationwas filtered

Quellen und Nachweise

ORD-Eintrag
ord-bbaa5d85196d44da98a1b9ee0d7f8902
Quelldatensatz
uspto-grants-2006_03
Patentnummer
US07008940B1

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