Tetrahydrofuran → 1-(8-Methyl-8-azabicyclo[3.2.1]octan-3-yl)-1H-indol-5-amine
Reaktionsgleichung
[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][n:7]([CH:11]3[CH2:12][CH:13]4[CH2:14][CH2:15][CH:16]([CH2:17]3)[N:18]4[CH3:19])[c:8]2[cH:9][cH:10]1.[C:20]([P:21]([C:22]([CH3:23])([CH3:24])[CH3:25])[C:26]([CH3:27])([CH3:28])[CH3:29])([CH3:30])([CH3:31])[CH3:32].[CH3:33][Si:34]([N-:37][Si:35]([CH3:36])([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Li+:42].[O:45]=[C:46]([CH:47]=[CH:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1)[CH:55]=[CH:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[O:63]=[C:64]([CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1)[CH:73]=[CH:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1.[O:81]=[C:82]([CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1)[CH:91]=[CH:92][c:93]1[cH:94][cH:95][cH:96][cH:97][cH:98]1.[O:99]1[CH2:100][CH2:101][CH2:102][CH2:103]1.[Pd:43].[Pd:44]>>[c:2]1([NH2:37])[cH:3][c:4]2[cH:5][cH:6][n:7]([CH:11]3[CH2:12][CH:13]4[CH2:14][CH2:15][CH:16]([CH2:17]3)[N:18]4[CH3:19])[c:8]2[cH:9][cH:10]1
