L-Ascorbic Acid → L-Gulonic acid, gamma-lactone
Reaktionsgleichung
[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([OH:6])=[C:3]1[OH:4]>O.[Pd]>[CH2:11]([OH:12])[C@H:9]([OH:10])[C@H:7]1[O:8][C:2](=[O:1])[C@@H:3]([OH:4])[C@H:5]1[OH:6]Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
To a solution of L-ascorbic acid in water is added Pd/C (10%). The mixture is subjected to hydrogenation in a Parr hydrogenator at 48 psi, 18° C. for about 2 to 3 days. The reaction mixture is filtered and the filtrate is concentrated in vacuo to afford L-gulonic γ-lactone, after drying at 50° C. in a vacuum oven for about 1 to 3 hours.
Aufarbeitung
- filtrationThe reaction mixture is filtered
- concentrationthe filtrate is concentrated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-bc05ac99a34448169fb70c3de32d753e
- Quelldatensatz
- uspto-grants-2006_07
- Patentnummer
- US07078438B2
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