Reaktionsgleichung
[Mg].[CH2:2](I)[CH3:3].C([Mg]I)C.[CH:9]12[CH2:18][CH:13]3[CH2:14][CH:15]([CH2:17][CH:11]([CH2:12]3)[C:10]1=[O:19])[CH2:16]2.C12CC3CC(CC(C3)C1O)C2>CCOCC.O1CCCC1>[CH2:11]([C:10]1([OH:19])[CH:9]2[CH2:16][CH:15]3[CH2:14][CH:13]([CH2:2][CH:3]1[CH2:17]3)[CH2:18]2)[CH3:12]Komponenten
8
Edukt 5
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
To 5 mL of ether was added 3.7 g (0.15 gram atom) of magnesium. To the mixture was added dropwise a solution of ethyl iodide (30 g, 0.19 mol) in ether (30 mL). The solution of ethylmagnesium iodide thus prepared was added dropwise to a solution of 2-adamantanone (20 g, 0.13 mol) in tetrahydrofuran (100 ml), and the mixture was stirred at room temperature overnight. GC analysis indicated that reduction products, i.e., 2-adamantanol and 2-ethyl-2-adamantanol were formed in 75% and 25%, respectively.
Quellen und Nachweise
- ORD-Eintrag
- ord-49046d439a0b4ff3b66b3de2c2459af8
- Quelldatensatz
- uspto-grants-2004_08
- Patentnummer
- US06770777B2
Verknüpfte Notizen
Wird geladen…