Water → 2,2'-(2,5-Dioxopiperazine-1,4-diyl)diacetic acid

HRID 1859259Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1859259
[C:1]([N:4]([CH2:9][C:10]([OH:12])=O)[CH2:5][C:6]([OH:8])=[O:7])(=[O:3])[CH3:2].[OH2:13]>C(O)(=O)C>[C:6]([CH2:5][N:4]1[CH2:2][C:1](=[O:3])[N:4]([CH2:5][C:6]([OH:8])=[O:7])[CH2:9][C:10]1=[O:12])([OH:7])=[O:13]

Komponenten

4

Edukt 2

HCID 962WaterHCID 10130190N-acetyliminodiacetic acid

Produkt 1

HCID 235108522,2'-(2,5-Dioxopiperazine-1,4-diyl)diacetic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Reaktionsbedingungen

Temperatur
195 °C

Versuchsvorschrift

N-acetyliminodiacetic acid (XVI) monohydrate (45 g) and varying amounts of water and acetic acid were heated at 175° C. or 195° C. for various periods of time. After cooling to room temperature, the mixture was filtered. The solid was washed with water (10 mL) and dried to give 1,4-di(carboxymethyl)-2,5-diketopiperazine. The table below shows the yields of solid under various conditions.

Aufarbeitung

  1. temperatureAfter cooling to room temperature
  2. filtrationthe mixture was filtered
  3. washThe solid was washed with water (10 mL)
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-17dfbc30ca9d4fd8b1bb1863a4fe8c94
Quelldatensatz
uspto-grants-2000_11
Patentnummer
US06153753

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