Lithium hydroxide, monohydrate → HCID 57659748, Verbindung

HRID 1897556Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1897556
[C:1]([C:5]1[S:9][C:8]([C:10]([O:12]CC)=[O:11])=[N:7][N:6]=1)([CH3:4])([CH3:3])[CH3:2].O.[OH-].[Li+:17]>C1COCC1.O>[C:1]([C:5]1[S:9][C:8]([C:10]([O-:12])=[O:11])=[N:7][N:6]=1)([CH3:4])([CH3:2])[CH3:3].[Li+:17]

Komponenten

5

Edukt 2

HCID 168937Lithium hydroxide, monohydrateHCID 2757341ethyl 5-tert-butyl-1,3,4-thiadiazole-2-carboxylate

Produkt 1

HCID 57659748HCID 57659748, VerbindungAusbeute 104,1 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A solution of ethyl 5-tert-butyl-1,3,4-thiadiazole-2-carboxylate (0.21 g, 1.0 mmol) and lithium hydroxide hydrate (42 mg, 1.0 mmol) in THF (2 mL) and water (2 mL) was stirred at room temperature for 18 hours. The solvent was removed under vacuum to give lithium 5-tert-butyl-1,3,4-thiadiazole-2-carboxylate (0.2 g) as a white solid which was used without further purification.

Aufarbeitung

  1. customThe solvent was removed under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-c18a0196ecd84d47aa546ae2a9eaba82
Quelldatensatz
uspto-grants-2013_08
Patentnummer
US08519137B2

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