5-Benzylidenehydantoin → 5-(Phenylmethyl)-2,4-imidazolidinedione

HRID 1905814

Reaktionsgleichung

Reaktionsgleichung von HRID 1905814
[CH:1](=[C:8]1[NH:12][C:11](=[O:13])[NH:10][C:9]1=[O:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[OH-].[Na+].[Pd]>[CH2:1]([CH:8]1[NH:12][C:11](=[O:13])[NH:10][C:9]1=[O:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 1

HCID 978575-Benzylidenehydantoin

Produkt 1

HCID 735655-(Phenylmethyl)-2,4-imidazolidinedioneAusbeute 79 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 14798Sodium HydroxideLösungsmittel

Versuchsvorschrift

190 g (1 mole) of 5-benzylidene-hydantoin are dissolved in 2 l of a N sodium hydroxide solution and 40 g of 5% palladium/charcoal catalyst are added. The mixture is hydrogenated at room temperature under atmospheric pressure and under shaking for 4 hours. The reaction mixture is worked up according to Example 6. Thus 150.2 g of the desired compound are obtained, yield 79%. Mp.: 187°-189° C.

Aufarbeitung

  1. additionare added
  2. customis hydrogenated at room temperature under atmospheric pressure

Quellen und Nachweise

ORD-Eintrag
ord-62ca1d88ee36474f8fd304eef8129797
Quelldatensatz
uspto-grants-1987_03
Patentnummer
US04647694

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