Cyclohexene → (2-Amino-5-hydroxyphenyl)acetonitrile

HRID 1941534Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1941534
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10]CC2C=CC=CC=2)=[CH:6][C:5]=1[CH2:18][C:19]#[N:20])([O-])=O.C1CCCCC=1>[Pd].C(O)C>[C:19]([CH2:18][C:5]1[CH:6]=[C:7]([OH:10])[CH:8]=[CH:9][C:4]=1[NH2:1])#[N:20]

Komponenten

5

Edukt 2

HCID 8079CyclohexeneHCID 14025389HCID 14025389, Verbindung

Produkt 1

HCID 19607200(2-Amino-5-hydroxyphenyl)acetonitrile

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A suspension of 5.4 g of 2-nitro 5-benzyloxyphenylacetonitrile, 5.4 ml of cyclohexene, 22 ml of ethanol and 3 g of 10% palladium on activated charcoal was refluxed for five hours. The suspension was then hot filtered and the filtrate evaporated. The residue was recrystallised from ethanol to produce dark beige crystals.

Aufarbeitung

  1. temperaturewas refluxed for five hours
  2. filtrationThe suspension was then hot filtered
  3. customthe filtrate evaporated
  4. customThe residue was recrystallised from ethanol
  5. customto produce dark beige crystals

Quellen und Nachweise

ORD-Eintrag
ord-9f85d6aa879d4d139c24221fd3f34af8
Quelldatensatz
uspto-grants-1997_12
Patentnummer
US05703266

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