5-(3,4-Dimethoxy-5-chlorophenyl)-2,4-pentadienoic acid → 5-(3,4-Dimethoxy-5-chlorophenyl)pentanoic acid

HRID 1974702Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1974702
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:12]=[CH:13][CH:14]=[CH:15][C:16]([OH:18])=[O:17])[CH:6]=[C:7]([Cl:11])[C:8]=1[O:9][CH3:10]>C(O)(=O)C.Cl.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:12][CH2:13][CH2:14][CH2:15][C:16]([OH:18])=[O:17])[CH:6]=[C:7]([Cl:11])[C:8]=1[O:9][CH3:10]

Komponenten

5

Edukt 1

HCID 542197795-(3,4-Dimethoxy-5-chlorophenyl)-2,4-pentadienoic acid

Produkt 1

HCID 193892435-(3,4-Dimethoxy-5-chlorophenyl)pentanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 23938PalladiumKatalysatorHCID 176Acetic AcidLösungsmittelHCID 313Hydrochloric AcidLösungsmittel

Versuchsvorschrift

A solution containing 6.2 g of the above product obtained in Example 32 was dissolved in a mixture of 30 ml of acetic acid and 3 ml of conc. hydrochloric acid. Palladium on charcoal catalyst (10% Pd) was added and the mixture was hydrogenated at normal pressure and room temperature. After filteration the solvents were evaporated in vacuo. Yield 3.2 g (55%), a viscous oil.

Aufarbeitung

  1. customwas hydrogenated at normal pressure and room temperature
  2. customAfter filteration the solvents were evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-6c0b69a068064ad1b48729193df73151
Quelldatensatz
uspto-grants-1994_02
Patentnummer
US05283352

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